Amanda Randles

Digital Library

ACM Distinguished Member

USA - 2023

Press Release

ACM Senior Member

USA - 2022

ACM Grace Murray Hopper Award

USA - 2017

citation

For developing HARVEY, a massively parallel circulatory simulation code capable of modeling the full human arterial system at subcellular resolution and fostering discoveries that will serve as a basis for improving the diagnosis, prevention, and treatment of human diseases.

Amanda has established an ambitious research program focused around the transformation of her circulatory modeling code HARVEY into a world-class research tool capable of making a direct clinical impact. HARVEY is a massively parallel circulatory simulation code capable of modeling the full human arterial system at subcellular resolution. Her work leverages high performance computing to solve biomedical problems. She has developed large-scale computational methods to study disease localization and progression to foster discoveries that will serve as a basis for improving the diagnosis, prevention, and treatment of human diseases.

Together with an interdisciplinary team of doctors, scientists, and computer scientists Amanda has developed several new methods of high-performance computer simulations for blood flow in arteries across multiple scales  from molecules to blood cells. She has been applying theories from cosmology to the simulation of the forces from the beating heart. She developed her own parallel application code (HARVEY) to model flow in microfluidic devices and aneurysms as well as in coronary arteries. Amanda's multi-disciplinary background in applied physics and of computational methods and parallelization strategies in computer science, serves her well in these endeavors.

Amanda has remained keenly aware of the need to translate computational results into actionable data doctors can use to improve patient outcomes, and has continued to build collaborations that will allow her use this new computational capability to bridge the gap from the computer to the clinic. Her cross-disciplinary approach will yield new insights into efficient fluid flow simulations for complex multi-scale systems that will be useful well beyond blood flow simulations.

Press Release

ACM-IEEE CS George Michael Memorial HPC Fellowships

USA - 2012

citation

Multiscale Hemodynamics

ACM-IEEE CS George Michael Memorial HPC Fellowships

USA - 2010

citation

Multiscale simulation of cardiovascular flows on the IBM Bluegene/P: full heart-circulation system at red-blood cell resolution

ACM-IEEE CS George Michael Memorial HPC Fellowships

USA - 2009

citation

Cardiovascular Disease